PARTNER AREA

Cardioplegia – a synonym for myocardial protection.

Custodiol® & More / Cardioplegia

Cardioplegia

Ideal conditions
in induced cardiac arrest.

Stress-free organ care allows
more focus on surgery.

Professor Bretschneider broadened the definition of “cardioplegia” to be a synonym for “myocardial protection”. The histidine-tryptophan-ketoglutarate solution (HTK) CUSTODIOL®, has been originally designed in order to provide a good myocardial protection

Brochure English - Custodiol for Cardioplegia and Heart transplantation

Download Folder
CUSTODIOL® for Cardioplegia and Heart transplantation

  • One of the two well-documented methods of cardioplegia: Professor Bretschneider’s and Professor Buckberg’s principles of cardioplegia are the only techniques, which offer a proven track record of published clinical studies
  • Nondepolarizing cardiac arrest: The low-to-moderate content of electrolytes (“intracellular”-type cardioplegic solution, 15mM sodium) mean less cellular stress during cold ischemia, especially since the cell membranes are protected by tryptophan
  • A single/initial application applied over the period of 6-8 minutes is sufficient for up to 180 minutes of myocardial ischemia
  • Superior energetic protection (ATP): Energy substrates and high buffering capacity offer the basis for both anaerobic energy supply during ischemia and full return to function upon reperfusion
Dr. Franz Köhler Chemie GmbH Logo

Copyright 2024
Dr. Franz Köhler Chemie GmbH
Werner-von-Siemens-Str. 14–28 | 64625 Bensheim
info@koehler-chemie.de | Phone: +49 6251 1083-0
Fax: +49 6251 1083-146 |
www.koehler-chemie.com